Members of the Bcl-2 protein family regulate apoptosis through interactions with several proteins.A Posters critical intrinsically disordered region (IDR) present in some members of the Bcl-2 family is essential for their function.Also, the structural and conformational plasticity of disordered regions is essential for the regulation of the Bcl-2 p
The immune system of human beings plays a pivotal role in guarding against different types of diseases.During the COVID-19 pandemic, people with weak immune systems were more likely to die.Regular physical activities and healthy food intake can significantly improve the immune system; however, people with a sedentary lifestyle and a busy job schedu
Low back pain is a major cause of disability worldwide that declines the quality of life; it poses a substantial economic burden for the patient and society.Intervertebral disc (IVD) degeneration (IDD) is the main cause of low back pain, and it is also the pathological basis of several spinal degenerative diseases, such as intervertebral disc herni
Trans-scaphoid lunate dislocation with volar displacement into the wrist/distal forearm is a devastating injury that most commonly occurs under situations of forceful impact to an extended wrist.Due to ligamentous disruption as well as fragile blood supply, these top Mayfield type 4 injuries are associated with significant morbidity and long-term s
Background Bicuspid aortic valve (BAV) is a congenital cardiac deformity, increasing the risk of developing calcific aortic valve disease (CAVD).The disturbance of hemodynamics can induce valvular calcification, but the mechanism has not been fully identified.Methods We constructed a finite element model (FEM) of the 5 Piece Queen Louvered Panel Be